BDBM25758 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide::Albetol::Labetolol::Normodyne::labetalol

SMILES CC(CCc1ccccc1)NCC(O)c1ccc(O)c(c1)C(N)=O

InChI Key InChIKey=SGUAFYQXFOLMHL-UHFFFAOYSA-N

Data  4 KI  2 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25758   

TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM25758(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
Affinity DataKi:  12.0nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University of Nottingham

LigandPNGBDBM25758(2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amin...)
Affinity DataKd:  23.5nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank